以第一或通讯作者在J HAZARD MATER、SCI CHINA LIFE SCI、PNAS、JBC、Biotech Adv、MOL NEUROBIOL等在内的国际著名或领域主流期刊发表SCI论文近60篇；以第一发明人获得发明专利授权8项；前后作为项目主持人获得国家自然科学基金项目8项、科技部“973”前期项目1项、“863”重点项目的子课题1项、云南省重大项目1项、基础研究重点项目2项；先后荣获云南省自然科学特等奖1次以及云南省自然科学一等奖2次。

主持科研项目
1.云南省科技厅重点研发项目，202403AC100007，肠道微生态诱发帕金森病的致病机制与中药防治研究，2024/01-2026/12，260万，子项目主持人。
2.国家自然科学基金委面上项目，32170184，线虫抵抗病原细菌中固有免疫与趋避行为的互作及其调控机制，2022/01-2025/12，58万，主持。
3.国家自然科学基金委地区项目，32060632，植物寄生线虫化感系统诱发逃避应答抵抗生防细菌的分子机制，2021/01-2024/12，35万，主持。
4.国家自然科学基金委地区项目，31460024，线虫病原细菌全基因组水平侵染分子机制研究，2015/01-2018/12，53万，结题，主持。
5.国家自然科学基金委面上项目，31370162，病原细菌与线虫互作的感知信号通路，2014/01-2017/12，82万，主持。
6. 国家自然科学基金委地区项目，31260262，酿酒酵母中Asr1p与肌动蛋白结合蛋白Crn1p新的相互作用，2013/01-2016/12，50万，主持。
7.国家自然科学基金委地区项目，30970065，食线虫细菌吸引宿主的分子机制研究，2010/01-2012/12，30万，主持。
8.国家自然科学基金委面上项目，30770070，食线虫芽胞杆菌侵染性胞外蛋白酶功能及协同作用研究，2008/01-2010/12，30万，主持。
9.国家自然科学基金委青年项目，30500338，侧孢芽孢杆菌侵染线虫分子机制，2016/1/-2016/12，10万，主持。
10.云南省科技厅基础研究重点项目，2019FA046，植物寄生线虫逃避病原细菌侵染的分子机制，2019/10-2022/11，50万，主持。
11.云南省科技厅基础研究重点项目，22014FA019，杀线虫芽孢杆菌侵染线虫分子机制研究，2014 /10-2017/11，50万，主持。
12.国家科技部“973”前期项目，2010CB134503，群体感应对线虫病原细菌致病基因的调控，2010/01-2012/12，65万，主持。

发表期刊论文目录
（1）Hua Bai#, Huan Gu#, Wenhui Zhou#, Guolin Shi, Jinyuan Yan, Wenhu Li, Yixin Li, Chidi Zhong, Ninghui Zhao*, Xiaowei Huang*. (2025) PD-like pathogenesis induced by intestinal exposure to microplastics:An in vivo study of animal models to a public health survey. Journal of Hazardous Materials. 486: 136974. (中科院一区TOP期刊，IF 12.2)
（2）Wenwen Liu#, Wenhui Zhou#, Peiji Zhao, Tingting Wu, Huan Gu, Yixin Li, Chidi Zhong, Hua Bai, Ninghui Zhao*, Xiaowei Huang*. (2025) PD-like pathogenesis of Caenorhabditis elegans infected by Nocardia farcinica intestinally and its molecular mechanism. Molecular Neurobiology 62: 2642-2654.
（3）Yuhong Li#, Hua Bai#, Wenwen Liu#, Wenhui Zhou, Huan Gu, Peiji Zhao, Man Zhu, Yixin Li, Xinyi Yan, Ninghui Zhao*, Xiaowei Huang*. (2024) Intergenerational epigenetic inheritance mediated by MYS-2/MOF in the pathogenesis of Alzheimer’s disease. iScience. 27: 110588.
（4）Man Zhu, Huan Gu, Hua Bai, Yinxin Li, Xiaowei Huang*. (2024) Role and Molecular Regulatory Mechanisms of Hippo Signaling Pathway in Caenorhabditis elegans and Mammalian Cell Models of Alzheimer’s Disease. Neurobiology of Aging. 134: 9-20.
（5）Yanli Zhao, Chidi Zhong, Yixin Li, Wenhui Zhou, Xiaowei Huang*. (2023) Novel Genes and Key Signaling Molecules Involved in the Repulsive Response of Meloidogyne incognita against Biocontrol Bacteria. Journal of Agricultural and Food Chemistry. 71: 19445−19456. (中科院一区TOP期刊， IF6.4)
（6）Hua Bai#, Hui Huang#, Ninghui Zhao, Huan Gu, Yixin Li, Wei Zou, Tingting Wu, Xiaowei Huang*. (2022) Small G Protein RAC-2 Regulates Forgetting via the JNK-1 Signaling Pathway in Caenorhabditis elegans. European Journal of Neuroscience. 56 (12): 6162-6173.
（7）Yanli Zhao#, Qinying Zhou#, Chenggang Zou, Keqin Zhang, Xiaowei Huang*. (2022) Repulsive response of Meloidogyne incognita induced by biocontrol bacteria and its effect on interspecific interactions. Frontiers in Microbiology, 13: 994941.
（8）Shanzhuang Niu, Wenhui Zhou, Yixin Li, Xiaowei Huang*. (2022) The signaling pathway of levamisole sensitive acetylcholine receptors involved in short term forgetting of Caenorhabditis elegans. Molecular Genetics and Genomics. 297: 1027-1038.
（9）Man Zhu, Yao Chen, Ninghui Zhao, Hua Bai, Keqin Zhang, Xiaowei Huang*. (2021) Multiple olfactory pathways contribute to the lure process of Caenorhabditis elegans by pathogenic bacteria. Science China-Life Sciences. 64 (8): 1346-1354. (中科院一区TOP期刊，IF9.5)
（10）Hua Bai, Wei Zou, Wenhui Zhou, Keqin Zhang, Xiaowei Huang*. (2021) Deficiency of innate immunity against P. aeruginosa enhances behavioral avoidance via the HECW-1/NPR-1 module in C. elegans. Infection and Immunity, 89 (10): e0006721
（11）Yuhong Li, Hui Huang, Man Zhu, Hua Bai, Xiaowei Huang*. (2021) Roles of the MYST family in the pathogenesis of Alzheimer’s disease via histone or non-histone acetylation. Aging and Disease, 12 (1): 132-142
（12）Jinyuan Yan #, Ninghui Zhao, #, Zhongshan Yang, Yuhong Li, Hua Bai, Wei Zou, Keqin Zhang, Xiaowei Huang*. (2020) A trade-off switch of two immunological memories in C. elegans reinfected by bacterial pathogens. Journal of Biological Chemistry, 295, 17323-17336 (Nature Index 期刊)
（13）Yuhong Li, Hua Bai, Hui Huang, Man Zhu, Donghua Zhang, Xiaowei Huang*. (2020) Forward genetic screening of a novel gene hmgs-1 Involved in Alzheimer Disease Pathogenesis in a transgenic Caenorhabditis elegans model. Biochemical and Biophysical Research Communication. 525 (1): 141-147.
（14）Man Zhu, Xiao’e Xu, Yuhong Li, Pengfei Wang, Shanzhuang Niu, Keqin Zhang, Xiaowei Huang*. (2019) Biosynthesis of the nematode attractant 2-heptanone and its co-evolution between the pathogenic bacterium B. nematocida and non-pathogenic bacterium B. subtilis. Frontiers in Microbiology, 10: 1489
（15）JI'ai Wang, Xiaowei Huang (共同第一), Shanzhuang Niu, Zhihong HU, Juan Li, Keqin Zhang*. (2019) Thioredoxin1 regulates conidia formation, hyphal growth, and trap formation in the nematode-trapping fungus Arthrobotrys oligospora. Annals of Microbiology. 69 （12）:1267-1274.
（16）杨永敏，郭健，李玉宏，黄晓玮*（2019) Rab蛋白在囊泡运输中的作用及影响. 中国科学， 49 (7): 788-797
（17）周沁莹, 朱曼, 黄辉, 黄晓玮* (2019) 植物寄生线虫化学感受系统研究进展, 49 (7): 828-838
（18）李慧慧，朱曼，李玉宏，黄晓玮*（2019）秀丽隐杆线虫Wnt途径异常对机械感知神经元的影响。中国科学，49（7）：916-920。
（19）Weipeng Liu, Zeying He, Feng Gao, Jinyuan Yan, Xiaowei Huang*. (2018) Sensor Kinase KinB and its Pathway-associated Key Factors Sense the Signal of Nutrition Starvation in Sporulation of Bacillus subtilis. MicrobiologyOpen, e00566
（20）Tong Liu, Dong-Wei Tian, Li-Juan Zou, Qi-Yan Can, Jin-Kui Yang, Jian-Ping Xu, Xiao-Wei Huang, Jia-Qin Xi, Ming-Liang Zhu, Ming He Mo, Ke-Qin Zhang. (2018) Quantitative proteomics revealed partial fungistatic mechanism of ammonia against conidial germination of nematode-trapping fungus Arthrobotrys oligospora ATCC24927. International Journal of Biochemistry & Cell Biology. 98: 104-112
（21）Xin-Li Sun; Yun-He Yang; Li Zhu; Fang-Yu Liu; Jian-Ping Xu; Xiao-Wei Huang; Ming-He Mo; Tong Liu; Ke-Qin Zhang. The lysine acetylome of the nematocidal bacterium Bacillus nematocida and impact of nematode on the acetylome. Journal of Proteomics, 2018, 177: 31-39
（22）邹伟，王琦，林容，黄晓玮* （2018）秀丽隐杆线虫病原逃避行为调控的分子机制研究进展。威廉希尔学报（ 自然科学版），2018， 40（6）：1277-1281。
（23）Donghua Zhang, Xin Zhu, Fan Sun, Shanzhuang Niu, Keqin Zhang, Xiaowei Huang*. (2017) The roles of actin cytoskeleton and actin-associated protein Crn1p in trap formation in Arthrobotrys oligospora. Research in Microbiology.168: 655-663
（24）Chunmei Zhang, Ninghui Zhao, Yao Chen, Donghua Zhang, Jinyuan Yan, Wei Zou, Keqin Zhang, Xiaowei Huang*. (2016) The Signaling Pathway of Caenorhabditis elegans Mediates Chemotaxis Response to the Attractant 2-Heptanone in a Trojan Horse-like Pathogenesis. Journal of Biological Chemistry. 291 (45): 23618–23627. (Nature Index 期刊)
（25）Qiuhong Niu, Lin Zhang, Keqin Zhang, Xiaowei Huang, Fengli Hui, Yunchao Kan, Lunguang Yao. （2016）Changes in intestinal microflora of Caenorhabditis elegans following Bacillus nematocida B16 infection. Scientific Reports. 6:20178. DOI: 10.1038/srep20178
（26）Juan Li, Chenggang Zou, Jianping Xu, Xinglai Ji, Xuemei Niu, Jinkui Yang, Xiaowei Huang, and Ke-Qin Zhang. (2015) Molecular Mechanisms of Nematode-Nematophagous Microbe Interactions: Basis for Biological Control of Plant-Parasitic Nematodes. Annu. Rev. Phytopathol. 53:67–95
（27）Zou W, Yan J, Zhao N, Ding J, Niu S, Zhang K, Huang X*. (2015) A novel role for the alcohol sensitive ring/PHD finger protein Asr1p in regulating cell cycle mediated by septin-dependent assembly in yeast. Biochemical and biophysical research communications, 458(1): 208-213.
（28）Jinyuan Yan, Wei Zou, Juan Fang, Xiaowei Huang, Feng Gao, Zeying He, Keqin Zhang and Ninghui Zhao. (2015). Eukaryote-like Ser/Thr protein kinase PrkA modulates sporulation via regulating the transcriptional factor σK in Bacillus subtilis. Frontiers in Microbiology 2015, 6: 382. doi: 10.3389/fmicb.2015.00382. eCollection.
（29）Xiaowei Huang*, K. Q. Zhang, Q. H. Niu, X. Wang, G. H. Li, C. G. Zou, X. D. Deng (2015) Predatory-prey relationship as well as the underlying molecular mechanism in the interaction between bacteria and nematodes. J Nematol. 47(3): 218–281
（30）Chunmei Zhang, Jinyuan Yan, Yao Chen, Chunyan Chen, Keqin Zhang*, Xiaowei Huang*. (2014) The olfactory signal transduction for attractive odorants in Caenorhabditis elegans. Biotechnology Advances 32:290-295. (中科院一区TOP期刊，IF 15.7)
（31）Zhongzhong Liu, Anto Budiharjo, Pengfei Wang, Hui Shi, Juan Fang, Rainer Borriss, Keqin Zhang, Xiaowei Huang*. (2013) The highly modified microcin peptide plantazolicin is associated with nematicidal activity of Bacillus amyloliquefaciens FZB42. Appl Microbiol Biotechnol, 97 (23): 10081-10090.
（32）Xidan Deng, Yunxia Tian, Qiuhong Niu, Xiao’e Xu, Hui Shi, Hanbo Zhang, Lianming Liang, Keqin Zhang*, Xiaowei Huang*. (2013) The ComP-ComA quorum system is essential for “Trojan horse” like pathogenesis in Bacillus nematocida. pLOS ONE 8 (10): e76920.
（33）Lin Zhang, Yongxin Fan, Haoying Zheng, Fengguang Du, Ke-qin Zhang, Xiaowei Huang, Linfeng Wang, Man Zhang, Qiuhong Niu (2013) Isolation and Characterization of a Novel Endoglucanase from a Bursaphelenchus xylophilus Metagenomic Library. PLoS One. 8(12): e82437.
（34）Wang J, Gao F, Liu Z, Qiao M, Niu X, Zhang K, Huang X*(通讯作者). (2012) Pathway and Molecular Mechanisms for Malachite Green Biodegradation in Exiguobacterium sp. MG2. PLoS ONE 7(12): e51808.
（35）Qiu-Hong Niu, Xiaowei Huang, Fengli Hui, Siliang Huang, Tao Ke, Ke-Qin Zhang, Lin Zhang. (2012) Colonization of Caenorhabditis elegans by Bacillus nematocida B16, a Bacterial Opportunistic Pathogen. J Mol Microbiol Biotechnol 22: 258–267.
（36）Qiuhong Niu, Yunxia Tian, Lin Zhang, Xiao’e Xu, Xuemei Niu, Zhenyuan Xia, Liping Lei, Ke-Qin Zhang, Xiaowei Huang*(通讯作者). (2011) Overexpression of the key virulence proteases Bace16 and Bae16 in Bacillus nematocida B16 to improve its nematocidal activity. Journal of Molecular Microbiology and Biotechnology. 21: 130-137
（37）Ji’ai Wang, Min Qiao, Kangbi Wei, Junmei Ding, Zhongzhong Liu, Ke-Qin Zhang, Xiaowei Huang*(通讯作者). (2011) Decolorizing activity of malachite green and its mechanisms involved in dye biodegradation by Achromobacter xylosoxidans MG1. Journal of Molecular Microbiology and Biotechnology. 20: 220-227
（38）Chun-Mei Zhang1, Xiao-Wei Huang (共同第一作者), Wen-Zheng Pan, Jing Zhang, Kang-Bi Wei, Hans-Peter Klenk, Shu-Kun Tang, Wen-Jun Li and Ke-Qin Zhang. (2011) Anoxybacillus tengchongensis sp. nov. and Anoxybacillus eryuanensis sp. nov., two novel facultatively anaerobic, alkalitolerant bacteria from hot springs. Int J Syst Evol Microbiol, 61：118-122
（39）Yang J, Wang L, Ji X, Feng Y, Li X, Zou C, Xu J, Ren Y, Mi Q, Wu J, Liu Sh, Liu Y, Huang X, Wang H, Niu X, Li J, Liang L, Ji K, Zhou W, Yu Z, Li G, Liu Y, Lei Li, Qiao M, Feng L, and Zhang KQ. (2011) Genomic and proteomic analyses of the fungus Arthrobotrys oligospora provide insights into nematode-trap formation. PLoS Pathogen. 9 (7): e1002179
（40）Niu QH, Huang XW (共同第一作者), Zhang L, Xu JP, Yang DM, Wei KB, Niu XM, An ZQ, Bennett W.J., Zou CG, Yang JK and Zhang KQ (2010) A Trojan horse mechanism of bacterial pathogenesis against nematodes. P NATL ACAD SCI USA 107: 16631-16636 (中科院一区TOP期刊，IF 10.6)
（41）Zou CG, Tao N, Liu WJ, Yang JK, Huang XW, Liu XY, Tu HH, Gan ZW, and Zhang KQ （2010） Regulation of subtilisin-like protease prC expression by nematode cuticle in the nematophagous fungus Clonostachys rosea. Environ Microbiol 12: 3243-3252
（42）Zou CG, Xu YF, Liu WJ, Zhou W, Tao N, Tu HH，Huang XW, Yang JK, and Zhang KQ （2010） Expression of a serine protease gene prC is up-regulated by oxidative stress in the fungus Clonostachys rosea: implications for fungal survival. PLoS One 5: e13386
（43）Liang L, Meng Z, Ye F, Yang J, Liu S, Sun Y, Guo Y, Mi Q, Huang X, Zou C, Rao Z, Lou Z, Zhang KQ （2010）The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes. FASEB J 24: 1391-1400
（44）Yan-Sheng Chu, Xue-Mei Niu,* Yan-Li Wang, Ji-Peng Guo, Wen-Zheng Pan, Xiao-Wei Huang, and Ke-Qin Zhang*. (2010) Isolation of putative biosynthetic inermediates of prenylated indole alkaloids form a thermophilic fungus Talaromyces thermophilus. Organic Letter, 16(19): 4356-4359
（45）Yang Jinkui, Gan Zhongwei, Lou Zhiyong, Tao Nan, Mi Qili, Liang Lianming, Sun Yuna, Guo Yu, Huang Xiaowei, Zou Chenggan, Rao Zihe, Meng Zhaohui,* Zhang Ke-Qin. (2010) Crystal structure and mutagenesis analysis of chitinase CrChi1 from the nematophagous fungus Clonostachys rosea in complex with the inhibitor Caffeine. Microbiology-SGM, 156: 3566-3574
（46）Ding, Junmei†, Xiaowei Huang† (共同第一作者), Na Zhao, Feng Gao, Qian Lu, and Ke-Qin Zhang. Response of Saccharomyces cerevisiae to ethanol stress involves the actions of protein Asr1p. 2010. Journal of Microbiology and Biotechnology. 20 (12): 1630-1636.
（47）WenZheng Pan, XiaoWei Huang (共同第一作者), KangBi Wei, ChunMei Zhang, DongMei Yang, JunMei Ding, KeQin Zhang.（ 2010）Diversity of thermophilic fungi in Tengchong Rehai National Park as revealed by ITS nucleotide sequence analyses. The Journal of Microbiology. 48 (2): 146-152.
（48）Junmei Ding, Xiaowei Huang (共同第一作者), Lemin Zhang, Na Zhao, Dongmei Yang, Keqin Zhang （2010） Tolerance and Stress Response to Ethanol in the Yeast Saccharomyces cerevisiae. Applied Microbiology and Biotechnology. 85(2): 253-263.
（49）Xiaowei HUANG, Yunxia LI, Yingzhen SU, Junmei DING, Keqin ZHANG*. (2009) The influences on conidiophore pleomorphism in Clonostachys rosea andRAPD analysis to the mutant producing only verticillate conidiophores. Annals of Microbiology. 59 (1): 39-44.
（50）Xiaowei Huang，Junwei Liu, Junmei Ding, Qiusheng He, Rui Xiong, Keqin Zhang. (2009) The investiagation of nematocidal activity in Stenotrophomonas maltophilia G2 and characterization of a novel virulence serine protease. Canadian Journal of Microbiology. 55 (8): 934-942.
（51）Xiaowei Huang, Yunxia Li, Qiuhong Niu, Keqin Zhang. (2007) Suppression subtractive hybridization (SSH) and its modifications in microbilogical research. Applied Microbiology and Biotechnology. 76: 753-760.
（52）Niu Qiuhong, Huang Xiaowei (共同第一作者), Zhang Lin, Lian Lihui, Li Yunxia, Li Juan, Zhang Keqin*. (2007) Functional identification of the gene bace16 from nematophagous bacterium Bacillus nematocida. Applied Microbiology and Biotechnology, 75: 141-148.
（53）Lin Chao, Yang Jinkui, Sun Hui, Huang Xiaowei, Wang Ruibin, Zhang Ke-Qin. (2007) Purification and characterization of a beta-1,3-glucanase from the novel mycoparasite Periconia byssoides. Biotechnology Letters, 29(4): 617-622.
（54）H Xiaowei, Z Ninghui, X Wei, T Yiping and X Linfeng. (2006) The experimental sutdy of hypoxia-inducible factor-1 and its target genes in spinal cord injury. Spinal Cord. 44: 35-43.
（55）Niu Qiuhong, Huang Xiaowei (共同第一作者), Zhang Lin, Li Yunxia, Li Juan, Yang Jinkui, Zhang Keqin* (2006) A neutral protease from Bacillus nematocida, another potential virulence factor in the infection against nematodes. Archives of Microbiology. 185: 439-448.
（56）Niu Qiuhong, Huang Xiaowei (共同第一作者)，Tian Baoyu, Yang Jinkui, Liu Jiang, Zhang Lin, Zhang Keqin*. (2006) Bacillus sp. B16 kills nematodes with a serine protease identified as a pathogenic factor. Applied Microbiology and Biotechnology. 69: 722-730.
（57）Jun Li, Jinkui Yang, Xiaowei Huang, Ke-Qin Zhang. (2006) Purification and characterization of an extracellular serine protease from Clonostachys rosea and its potential as a pathogenic factor. Process Biochemisty, 41: 925-929
（58）Hui Sun, Jinkui Yang, Chao Lin, Xiaowei Huang, Ruihuan Xing, Ke-Qin Zhang. (2006) Purification and properties of a ß-1,3-glucanase from Chaetomium sp. that is involved in mycoparasitis. Biotechnology Letters 28: 131-135.
（59）X. Huang, B. Tian, Q. Niu, K. Zhang*.(2005) An extracellular protease from Brevibacillus laterosporus G4 without parasporal crystal serve as pathogenetic factor in the infection against nematodes. 2005, Research in Microbiology. 156: 719-727.
（60）Huang Xiaowei, Niu Qiuhong et al. (2005) Bacillus nematocida sp.nov., a novel bacterial strain with nematotoxic activity isolated from soil in Yunnan, China, Systematic and Applied Microbiology. 28: 323-327.
（61）Mo MH, Huang XW, Zhou W, Huang Y, Hao YE, Zhang KQ. (2005) Arthrobotrys yunnanensis sp nov., the fourth anamorph of Orbilia auricolor. Fungal Diversity, 18:107-115
（62）Jinkui Yang, Xiaowei Huang, Baoyu Tian, Miao Wang, Qiuhong Niu, Keqin Zhang. (2005) Isolation and characterization of a serine protease from the nematophagous fungus, Lecanicillium psalliotae, displaying nematicidal activity. Biotechnology Letter, 27:1123-1128
（63）Jinkui Yang, Xiaowei Huang, Baoyu Tian, Hui Sun, Junxin Duan, Wenping Wu, Keqin Zhang. (2005) Characterization of an extracellular serine protease gene from the nematophagous fungus Lecanicillium psalliotae. Biotechnology Letter, 27: 1329-1334
（64）Xu Jin, Mo Ming-He, Huang Xiao-Wei, Zhang Ke-Qin. (2005) Improvement on genetic transformation in the nematode-trapping fungus Arthrobotrys oligospora and its quantification on dung samples. Mycophathology, 159: 533-538.
（65）Xu Jin, Mo Ming-He, Zhou Wei, Huang Xiao-Wei and Zhang Ke-Qin. (2005) Transformation and Mutagenesis of the Nematode-trapping Fungus Monacrosporium sphaeroides by Restriction Enzyme-mediated Integration (REMI). The Journal of Microbiology.43 (5): 417-423.
（66）X. Huang, N. Zhao, K. Zhang. (2004) The Extracellular Enzymes Serve as Virulent Factors in Nematophagous Fungi Involved in The Infection of Host. Research in Microbiology, 155：811-816.